AAFC is requesting proposals for the conduct of chemical analysis for pesticide residues on crop samples collected from field trials at several Canadian locations, in accordance with the requirements of the Organization for Economic Co-operation and Development (OECD) Principles of Good Laboratory Practices (GLP) (rev 1997), study plans (Appendix A – Annex 2) and Health Canada’s Pest Management Regulatory Agency regulatory directive, DIR98-02 “Residue Chemistry Guidelines” (Regulatory Directive: Residue Chemistry Guidelines - Canada.ca).Only the analytical methods as in the list of projects in Annex 1 of this Appendix can be used.The methods may be obtained as indicated below:Project 1: AAFC22-001R, AAFC22-002R (broflanilide)Method # 2017/7016349: Validation of BASF Method Number D1417/01 for the determination of residues of BAS 450 I and its metabolites S(PFP-OH)-8007 and DM-8007 in wheat (grain), dry beans (seed), tomato (whole fruit), citrus (whole fruit), soybean (seed) and coffee (grain) using LCMS/MS. (Including Amendment No.1). BASF Study Number 772495. Veiga, A. and Jose, W; 2017.Methods belonging to BASF Canada Inc., must be requested fromChristine Headon, Tel: 416-453-3577; email: c••••••••@••••.comProject 2: AAFC22-031R, AAFC22-032 (pyrethrins and piperonyl butoxide)Method # GLP-MTH-074: Determination of Pyrethrins and Piperonyl Butoxide (PBO) in Crops, GLP-MTH-074 Original, M.R. Huebner, Golden Pacific Laboratories, May 24, 2010.Method belonging to McLaughin Cormley King Company, must be requested from Amy McNeilly, Tel: 763-593-3443; email: a••••••••@•••.com Project 3: AAFC20-037R, AAFC20-038R, AAFC20-047R (flazafulfuron)Method # S09-03106: Flazasulfuron – Validation of analytical method for flazasulfuron in crops, Study Code: S09-03106, S. Oppilliart, Eurofins|ADME Biosciences, 10 Dec 2009.Methods belonging to ISK Biosciences Corporation, must be requested from Karol Krey, Tel: 216-372-2569; email: k••••@•••••.comProject 4: AAFC20-034R (flumioxazin)Method # RM-30A-3: Determination of flumioxazin residues in crops, RM-30A-3, Valent USA Corporation, 18 Mar 2003.Method belonging to Valent Canada, must be requested from Beth Connor, Tel: 519-830-7837; email: b••••••••@••••••.com Project 5: AAFC22-010R (oxyfluorfen)Method 1 # 34-95-111: 1. Enforcement Residue Analytical Method for GOAL Herbicide (oxyflurofen) in Crop Commodities with GC/MS Confirmation, Report No.: 34-95-111, D.A. Martin, Q. Zang, 29 Apr 1996Method 2 # GRM 07.05: Determination of Residues of Oxyfluorfen in Agricultural Commodities by Gas Chromatography with Negative-Ion Chemical Ionization Mass Spectrometry, GRM 07.05, E.L. Olberding, B.M. Wendelburg, Dow AgroSciences, 25 Apr 2007.Methods belonging to NUFARM Agriculture Inc., are available in Appendix A, Annex 3 a&bProject 6: AAFC22-016R (clethodim)Method # Meth-156: Determination of Clethodim Residues (Common Moiety) in Crops, Animal Tissues, Milk and Eggs, Meth-156 Original, Morse Laboratories Inc., 27 Dec 2002.Method belonging to UPL AgroSolutions Canada Inc., must be requested from Nicole Gentner Tel: 819-291-0036; email: n••••••••@•••••••.comFrozen samples will be shipped to the successful bidder(s) (laboratory) upon harvest from ongoing field trials and/or from the AAFC Analytical Laboratory. Anticipated harvest dates are indicated on the List of Projects (Appendix A, Annex 1). The exact shipping dates will be determined after the contract is awarded. Storage stability data will be required if, at the time of analysis, samples have been stored longer than the storage stability timeframe indicated on the List of Projects.With the exception of modifications necessary to adapt the methods to different crop fractions, AAFC expects the methods to be followed as written. This applies specifically to the equipment (detector) used to determine the residue definition. If, however, upon review of the method provided, the bidder believes that a different detector can be used, a rationale for the modification must be clearly indicated in the proposal and all impacts or changes in the procedures on the reference method indicated. Upon awarding contracts, all proposed modifications must be thoroughly discussed with the Study Director and approved prior to method validation.For the purpose of preparing proposals, it is not a requirement to bid on all Projects. Proposals must be submitted on the basis of Project number and not by study number. A Project consists of all the respective studies specific to a given Project number, the active ingredient, the commercial product, the crop(s), the number of trials conducted and the number of samples per trial (treated and untreated). The list of Projects for which proposals are being sought is included in Appendix A, Annex 1. A study plan amendment template outlining analytical procedures to be followed is included in Appendix A, Annex 2. The Residue Analysis Application Form (Appendix C – Annex 1) must be completed for each Project for which a bid is being made.As field trials are subject to the forces of nature throughout the growing season and possible changes in regulatory requirements, there is a possibility in either the cancellation of trials or changes in the number of samples required for residue analysis. This may result in the need to amend this RFP or to adjust contracts to reflect changes.Bids must be in Canadian dollars. Evaluations for cost per point are calculated on the total cost of the individual Project, excluding HST. HST can only be collected if your company has a HST registration number. For further information please contact Canada Revenue Agency at:http://www.ccra-adrc.gc.ca/sitemap-e.html#tax.The failure to provide bids in Canadian dollars will make the proposal non-compliant. AAFC will reject any bid not in Canadian currency.It is expected that AAFC will have to contract with several different companies to complete the identified laboratory analysis for the specified Projects. However, the degree of work that will be contracted is dependent upon many factors, including the response level to this RFP.
