Trade Agreement: Agreement on Internal Trade (AIT)
Tendering Procedures: The bidder must supply Canadian goods
and/or services
Attachment: None
Competitive Procurement Strategy: Best Overall Proposal
Comprehensive Land Claim Agreement: No
Nature of Requirements:
1. TITLE:
ADVANCED MESENCHYMAL STEM CELL DEVELOPMENT
2. SECURITY REQUIREMENTS:
2.1 The following security requirements apply and form part of
the Contract.
Security Requirement for Canadian Supplier: PWGSC File
#W7702-155729
2.1.1 The Contractor/Offeror must, at all times during the
performance of the Contract/Standing Offer, hold a valid
Designated Organization Screening (DOS), issued by the Canadian
Industrial Security Directorate (CISD), Public Works and
Government Services Canada (PWGSC).
2.1.2 The Contractor/Offeror personnel requiring access to
sensitive work site(s) must EACH hold a valid RELIABILITY
STATUS, granted or approved by CISD/PWGSC.
2.1.3 Subcontracts which contain security requirements are NOT
to be awarded without the prior written permission of CISD/PWGSC.
2.1.4 The Contractor/Offeror must comply with the provisions of
the:
(a) Security Requirements Check List and security guide (if
applicable), attached at Annex "C" of the Solicitation;
(b) Industrial Security Manual (Latest Edition).
3. REQUIREMENT:
Defence Research and Development Canada - Suffield Research
Station has a project to support the ongoing efforts to provide
the Canadian Armed Forces with medical countermeasures to
protect them against hazards while on operations.
Adult stem cells are therapeutic tools with promise in
accelerating healing and tissue regeneration, and as engineered
cells that produce therapeutic molecules. Mesenchymal stem
cells are non-embryonic adult cells sourced in this case from
umbilical cord tissue (usually treated as waste) following
normal births. This contract will NOT involve tissue or cell
collection; cells will be obtained from commercial suppliers.
Our aim is to develop mesenchymal stem cells (MSC) to address
capability gaps in medical countermeasures (MCMs) available to
the Canadian Armed Forces. In clinical trials, human MSC have
consistently proven safe for transplant, and regulatory approval
for MSC-derived therapeutic products has already been
established.
This effort will extend our understanding of the utility of
mesenchymal stem cells as therapeutic tools, using a combination
of native cells, recombinant protein expression constructs in
MSC, and cell or media extracts. Some basic properties of MSC
will be characterized, such as in vivo survival, in vitro
stability on expansion in culture, genetic stability in extended
culture, and differentiation versus culture condition or time.
To qualify a bid will have to consist of no less than 80% of
goods and/or services of Canadian origin.
WARNING: FACSIMILE BIDS WILL NOT BE ACCEPTED due to the nature
of this solicitation.
4. EVALUATION AND SELECTION:
Evaluation: Mandatory and point rated technical and management
evaluation criteria are included in Annex "F" of the
solicitation.
Contractor selection: The responsive bid with the highest number
of points will be recommended for award of a contract, provided
that the total evaluated price does not exceed the budget
available for this requirement.
5. OWNERSHIP OF INTELLECTUAL PROPERTY:
Any intellectual property arising from the performance of the
Work under the Contract will vest in the Contractor.
6. CANADA'S MAXIMUM FUNDING AND ADDITIONAL CONTRACTOR FUNDING
Canada's maximum funding available for the contract resulting
from the bid solicitation is $490,000.00 [Contract Term:
$360,000.00; Option Period: $130,000.00] (Applicable Taxes
extra, as appropriate). Any cost in excess of the maximum
funding will be construed as a Contractor's commitment of
additional funding to the Contract. This disclosure does not
commit Canada to pay the maximum funding available.
7. PERIOD OF CONTRACT:
It is anticipated that any contract will be effective from date
of Contract to 2017-03-31 inclusive, with the irrevocable option
to extend the term of the Contract by up to one (1) additional
one (1) year periods (Period 1: 2017-04-01 to 2018-03-31).
Contracting Authority
Lorraine Jenkinson
Supply Specialist
Public Works and Government Services Canada
Acquisitions Branch, Western Region
ATB Place ATB, North Tower
10025 Jasper Avenue, 5e étage
Edmonton, AB T5J 1S6
Telephone: (780) 497-3593 Facsimile: (780) 497-3510
E-mail address: L••••••••@••••••••.••.ca
Delivery Date: Above-mentioned
The Crown retains the right to negotiate with suppliers on any
procurement.
Documents may be submitted in either official language of Canada.
