Notice to purchase a z-Movi Cell Avidity Analyzer with mini incubator from Lumicks USA. Sole Source justifications as below:
The z-Movi® Cell Avidity Analyzer is a unique instrument to measure cell avidity, a key parameter for
the development of immuno-oncology therapies. z-Movi directly quantifies cell–cell binding strength at
single-cell resolution of hundreds of cells simultaneously by applying contactless acoustic forces
(based on AFS technology). The binding avidity measured by the z-Movi combines reproducibility and
speed of biophysical methods with the predictiveness of a functional assay.
The LUMICKS B.V. is the only company currently offering instruments for measuring cell avidity at
cellular level of hundreds of cells simultaneously. z-Movi technologies were invented by LUMICKS’
founders and employees and published in Nature Methods (online November 24th 2014) and Cell
Reports (September 11, 2018).
LUMICKS holds several patents on these technologies, making it the sole provider of any such
instrumentation. Relevant patents and pending patent applications are listed below.
- Molecular manipulation system and method: US10941437, EP3008506
- Method and system for studying biological cells: US11207684, US20220118453, EP3535576,
CN110140050, JP2020511126, CA3042444
- Probing mechanical properties of biological matter: US20210247291, EP3788360
- Determining interactions between cells based on force spectroscopy: WO2021089654
- Methods and systems for manipulating a particle: WO2022010356
- Method and system for collecting one or more cellular bodies: WO2022043467
- Method and system for studying objects, in particular biological cells: WO2022045892
- Sorting of cellular bodies based on force spectroscopy: WO2022050839
- Methods and systems for detecting particle occupancy: WO2022066011
- Determining interactions between cellular bodies and a functionalized wall surface:
WO2022066009
- Determination of physical properties of cellular bodies based on acoustic force spectroscopy:
WO2022075844
- System and method for loading a microfluidic chip: WO2022075848
- Improved detection of lymphocyte - target cell interaction: WO2022086328
